Photobiomodulation
Photobiomodulation (PBM), also known as low-level light therapy, utilizes red to near-infrared light to stimulate cellular activity. When applied to the brain, PBM has been shown to enhance neuronal metabolism and energy production, thereby promoting a state conducive to neuroplasticity—the brain's ability to reorganize itself by forming new neural connections.
The primary mechanism involves the absorption of light by mitochondrial cytochrome c oxidase, leading to increased ATP production. This boost in cellular energy supports various neuroprotective processes, including
anti-inflammatory and antioxidant responses, as well as the stimulation of neurogenesis and synaptogenesis.
By enhancing these metabolic and protective pathways, PBM effectively opens a "neuroplasticity window," a period during which the brain exhibits heightened plasticity. This state facilitates positive changes in neuronal networks, making PBM a promising adjunctive therapy for conditions requiring neural rehabilitation or cognitive enhancement.
Recent studies have demonstrated that transcranial PBM can improve cognitive functions, such as visual working memory, further supporting its role in modulating neuroplasticity. (science.org)
Incorporating PBM into therapeutic protocols may thus offer a non-invasive means to prepare the brain for adaptive changes, leveraging the neuroplasticity window to achieve desired outcomes in neural health and function.
Learn about Brain Energy: Brain Energy & mitochondria: The Cellular Engine Behind Healing
Photobiomodulation (PBM)—the brain gains access to a renewed source of vitality and resilience.
At the Brain Institute, we integrate findings from mitochondrial medicine, stress neurobiology, and precision brain therapies to understand and support this powerful brain-body connection. Our approach includes:
Assessing mitochondrial health as a marker of brain energy availability
Applying PBM to activate mitochondrial respiration and promote neuroplasticity
Monitoring changes in mental clarity, emotional stability, and resilience
Photobiomodulation stimulates cytochrome c oxidase—an enzyme critical for mitochondrial energy production. By enhancing this process, PBM helps restore the organized flow of energy through the brain’s networks, creating conditions for healing and improved function.
We view mitochondria as bioenergetic bridges between the body and mind. When supported with precision tools like PBM, they enable the brain to recalibrate, self-regulate, and thrive.
Biohacking workshop: Learn how to combine Photiomodulation Brain training to harness PBM induced Neuroplasticity